Article
Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status.
British journal of cancer - 1 Nov 2020
Olafsdottir Elinborg J, Borg Ake, Jensen Maj-Britt, Gerdes Anne-Marie, Johansson Anna L V, Barkardottir Rosa B, Johannsson Oskar T, Ejlertsen Bent, Sønderstrup Ida Marie Heeholm, Hovig Eivind, Lænkholm Anne-Vibeke, Hansen Thomas van Overeem, Olafsdottir Gudridur H, Rossing Maria, Jonasson Jon G, Sigurdsson Stefan, Loman Niklas, Nilsson Martin P, Narod Steven A, Tryggvadottir Laufey
Abstract excerpt
BACKGROUND: The natural history of breast cancer among BRCA2 carriers has not been clearly established. In a previous study from Iceland, positive ER status was a negative prognostic factor. We sought to identify factors that predicted survival after invasive breast cancer in an expanded cohort of BRCA2 carriers. METHODS: We studied 608 women with invasive breast cancer and a pathogenic BRCA2 mutation (variant)...
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