Article
Binding Sites in the EFG1 Promoter for Transcription Factors in a Proposed Regulatory Network: A Functional Analysis in the White and Opaque Phases of Candida albicans.
G3 (Bethesda, Md.) - 1 Jun 2016
Pujol Claude, Srikantha Thyagarajan, Park Yang-Nim, Daniels Karla J, Soll David R
Abstract excerpt
In Candida albicans the transcription factor Efg1, which is differentially expressed in the white phase of the white-opaque transition, is essential for expression of the white phenotype. It is one of six transcription factors included in a proposed interactive transcription network regulating white-opaque switching and maintenance of the alternative phenotypes. Ten sites were identified in the EFG1 promoter that...
Topics
- Alleles
- Binding Sites
- Candida albicans
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression
- Gene Expression Regulation, Fungal
- Gene Regulatory Networks
- Genes, Reporter
- Mutation
- Promoter Regions, Genetic
- Protein Binding
- Sequence Deletion