Transcriptional loops meet chromatin: a dual‐layer network controls white–opaque switching in <i>Candida albicans</i>

Abstract excerpt

The human pathogen Candida albicans is able to undergo a reversible switch between two distinct cell types called white and opaque, which are considered different transcriptional states of cells harbouring identical genomes. The present model of switching regulation includes the bistable expression of a master switch gene that is controlled by multiple transcriptional feedback loops. Here, we show that...

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