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Article

Temporal anatomy of an epigenetic switch in cell programming: the white‐opaque transition of C. albicans

2 Aug 2010

Abstract excerpt

The human pathogen Candida albicans undergoes a well-defined switch between two distinct cell types, named 'white' and 'opaque'. White and opaque cells differ in metabolic preferences, mating behaviours, cellular morphologies and host interactions. Each cell type is stable through many generations; switching between them is rare, stochastic and occurs without any known changes in the primary sequence of the...

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PMID: 20735781
DOI: 10.1111/j.1365-2958.2010.07331.x

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Temporal anatomy of an epigenetic switch in cell programming: the white‐opaque transition of C. albicansPMID 20735781Read ↗

Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans.Semantic proximity Read ↗

Epigenetic properties of white–opaque switching in <i>Candida albicans</i> are based on a self-sustaining transcriptional feedback loopSemantic proximity Read ↗

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Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.Semantic proximity Read ↗

Structure of the transcriptional network controlling white-opaque switching in Candida albicans.Semantic proximity Read ↗

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