Multiple molecular events underlie stochastic switching between 2 heritable cell states in fungi.

Abstract excerpt

Eukaryotic transcriptional networks are often large and contain several levels of feedback regulation. Many of these networks have the ability to generate and maintain several distinct transcriptional states across multiple cell divisions and to switch between them. In certain instances, switching between cell states is stochastic, occurring in a small subset of cells of an isogenic population in a seemingly...

Topics

• Candida albicans
• Cell Differentiation
• Fungal Proteins
• Gene Expression Regulation, Fungal
• Gene Regulatory Networks
• Phenotype
• Transcription Factors