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Article

Mutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma.

Head & neck - 1 Aug 2014

McBride Sean M, Rothenberg S Michael, Faquin William C, Chan Annie W, Clark John R, Ellisen Leif W, Wirth Lori J

Abstract excerpt

BACKGROUND: With prior studies having looked at unselected cohorts, we sought to explore the mutational landscape in a high-risk group of head and neck squamous cell carcinoma (HNSCC) tumors. METHODS: A multiplexed polymerase chain reaction (PCR) assay evaluating 68 loci in 15 genes was performed...

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Topics

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Share to Class I Phosphatidylinositol 3-Kinases
Share to Genes, Neoplasm
Share to Head and Neck Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multiplex Polymerase Chain Reaction

Share to Mutation Rate

Share to Proto-Oncogene Proteins c-akt

Share to Squamous Cell Carcinoma of Head and Neck

Source

Open in PubMed Open full text

Identifiers

PMID: 23852799
DOI: 10.1002/hed.23430
PMCID: PMC4096067

Genes

AKT1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23852799-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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