Article
Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 Nov 2010
Bruckman Karl C, Schönleben Frank, Qiu Wanglong, Woo Victoria L, Su Gloria H
Abstract excerpt
OBJECTIVES: The development of oral squamous cell carcinoma (OSCC) is a complex, multistep process. To date, numerous oncogenes and tumor-suppressor genes have been implicated in oral carcinogenesis. Of particular interest in this regard are genes involved in cell cycling and apoptosis, such BRAF...
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