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Article

Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 Nov 2010

Bruckman Karl C, Schönleben Frank, Qiu Wanglong, Woo Victoria L, Su Gloria H

Abstract excerpt

OBJECTIVES: The development of oral squamous cell carcinoma (OSCC) is a complex, multistep process. To date, numerous oncogenes and tumor-suppressor genes have been implicated in oral carcinogenesis. Of particular interest in this regard are genes involved in cell cycling and apoptosis, such BRAF, KRAS, and PIK3CA genes. STUDY DESIGN: Mutations of BRAF, KRAS, and PIK3CA were evaluated by direct genomic sequencing...

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Source

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Identifiers

PMID: 20813562
DOI: 10.1016/j.tripleo.2010.05.002
PMCID: PMC2987741

Genes

BRAF
KRAS

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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