Article
Hotspot mutations in common oncogenes are infrequent in nasopharyngeal carcinoma.
Oncology reports - 1 Oct 2014
Jiang Ning, Liu Na, Yang Fan, Zhou Qiming, Cui Ruixue, Jiang Wei, He Qingmei, Li Wenfei, Guo Ying, Zeng Jing, Yun Jingping, Chen Xinchun, Zhou Boping, Sun Ying, Wang Huiyun, Chen Zhuo G, Ma Jun
Abstract excerpt
Oncogene mutations contribute to carcinogenesis and can provide potential therapeutic targets for clinical anticancer management. However, oncogene mutation patterns in nasopharyngeal carcinoma (NPC) have yet to be fully elucidated. To gain insight into mutation patterns in NPC, a high-throughput OncoCarta panel assay was used to determine 238 hotspot mutations across 19 common oncogenes in 8 NPC cell lines and...
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