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Article

Female-specific hypertension loci on rat chromosome 13.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 2013

Hoffman Matthew J, Flister Michael J, Nunez Lizbeth, Xiao Bing, Greene Andrew S, Jacob Howard J, Moreno Carol

Abstract excerpt

A 3.7-Mb region of rat chromosome 13 (45.2-49.0 Mb) affects blood pressure (BP) in females only, indicating the presence of sex-specific BP loci in close proximity to the Renin locus. In the present study, we used a series of Dahl salt-sensitive/Mcwi-13 Brown Norway congenic rat strains to further resolve BP loci within this region. We identified 3 BP loci affecting female rats only, of which the 2 smaller loci...

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Identifiers

PMID: 23817491
DOI: 10.1161/HYPERTENSIONAHA.113.01708
PMCID: PMC3870583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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