Article
Congenic mapping and sequence analysis of the Renin locus.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 2013
Flister Michael J, Hoffman Matthew J, Reddy Prajwal, Jacob Howard J, Moreno Carol
Abstract excerpt
Renin was the first blood pressure (BP) quantitative trait locus mapped by linkage analysis in the rat. Subsequent BP linkage and congenic studies capturing different portions of the renin region have returned conflicting results, suggesting that multiple interdependent BP loci may be residing in the chromosome 13 BP quantitative trait locus that includes Renin. We used SS-13(BN) congenic strains to map 2 BP loci...
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