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Article

Gene Deficiency in Activating Fcγ Receptors Influences the Macrophage Phenotypic Balance and Reduces Atherosclerosis in Mice.

PloS one - 1 Jan 2013

Mallavia Beñat, Oguiza Ainhoa, Lopez-Franco Oscar, Recio Carlota, Ortiz-Muñoz Guadalupe, Lazaro Iolanda, Lopez-Parra Virginia, Egido Jesus, Gomez-Guerrero Carmen

Abstract excerpt

Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients. We hypothesize that specific Fcγ receptors for IgG constant region participate in atherogenesis by regulating the inflammatory state of lesional macrophages. In vivo we examined the role of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23805273
DOI: 10.1371/journal.pone.0066754
PMCID: PMC3689671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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