Human receptors for immunoglobulin G: Key elements in the pathogenesis of rheumatic disease

Abstract excerpt

Receptors for immunoglobulin constitute the link between humoral and cellular aspects of the immune cascade and play an integral part in the process by which opsonized material, both foreign and endogenous, is identified and destroyed. Recent advances in our understanding of the physiology of these cell-based binding sites for antibody, termed Fc receptors (FcR) because they interact with the constant region (Fc...

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