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Article

CD40L and Its Receptors in Atherothrombosis—An Update

20 Jun 2017

Abstract excerpt

CD40L (CD154), a member of the tumor necrosis factor superfamily, is a co-stimulatory molecule that was first discovered on activated T cells. Beyond its fundamental role in adaptive immunity-ligation of CD40L to its receptor CD40 is a prerequisite for B cell activation and antibody production-evidence from more than two decades has expanded our understanding of CD40L as a powerful modulator of inflammatory...

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PMID: 28676852
DOI: 10.3389/fcvm.2017.00040

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