Article
Correlation between acetylator phenotypes and genotypes of polymorphic arylamine N-acetyltransferase in human liver.
The Journal of biological chemistry - 5 Aug 1990
Deguchi T, Mashimo M, Suzuki T
Abstract excerpt
Southern blot analysis was performed with genomic DNAs from 86 human subjects using the 32P-labeled cDNA for polymorphic arylamine N-acetyltransferase (EC 2.3.1.5) in human liver recently cloned in our laboratory. Three types of N-acetyltransferase gene were identified. Gene 1 contains a 5.5-kilobase (kb) KpnI fragment with a BamHI site; gene 2 contains a 5.5-kb KpnI fragment without a BamHI site; and gene 3...
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