Correlation between acetylator phenotypes and genotypes of polymorphic arylamine N-acetyltransferase in human liver.

Article

Correlation between acetylator phenotypes and genotypes of polymorphic arylamine N-acetyltransferase in human liver.

The Journal of biological chemistry - 5 Aug 1990

Deguchi T, Mashimo M, Suzuki T

Abstract excerpt

Southern blot analysis was performed with genomic DNAs from 86 human subjects using the 32P-labeled cDNA for polymorphic arylamine N-acetyltransferase (EC 2.3.1.5) in human liver recently cloned in our laboratory. Three types of N-acetyltransferase gene were identified. Gene 1 contains a 5.5-kilo...

Topics

Acetyltransferases
Arylamine N-Acetyltransferase
Blotting, Southern
DNA
Genotype
Humans
Leukocytes
Liver
Phenotype
Polymorphism, Genetic
Restriction Mapping

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.