Article
An improved method for genotyping of N-acetyltransferase polymorphism by polymerase chain reaction.
The Japanese journal of human genetics - 1 Jun 1993
Abe M, Suzuki T, Deguchi T
Abstract excerpt
Polymorphic N-acetyltransferase in human liver catalyzes N-acetylation of various arylamine-containing drugs and environmental chemicals. To accelerate the pharmacogenetic and ecogenetic studies of N-acetyltransferase polymorphism, we have developed a rapid and simple method for genotyping using a polymerase chain reaction based restriction fragment length polymorphism. This method distinguishes four kinds of...
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