Molecular genotyping of N-acetylation polymorphism to predict phenotype.

doi:10.1007/BF00210758

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Molecular genotyping of N-acetylation polymorphism to predict phenotype.

Human genetics - 1 Jan 2000

Mashimo M, Suzuki T, Abe M, Deguchi T

Abstract excerpt

N-acetylation polymorphism is one of the representative pharmacogenetic traits that underlie interindividual and interethnic differences in response to xenobiotics. To develop a practical genotyping method to predict acetylator phenotype, we studied the conditions for accurate phenotyping, and identified the phenotype in 51 Japanese. Then we performed Southern blot analysis of genomic DNA from these subjects...

Topics

Acetylation
Adult
Alleles
Arylamine N-Acetyltransferase
Asian People
Biotransformation
Blotting, Southern
Chromatography, High Pressure Liquid
Female
Genotype
Humans
Isoniazid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Japan

Male

Middle Aged

Phenotype

Polymorphism, Genetic

Predictive Value of Tests

Source

Open in PubMed

Identifiers

PMID: 1427770
DOI: 10.1007/BF00210758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1427770-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genotyping of N-acetylation polymorphism to predict phenotype.PMID 1427770Read ↗

Correlation between acetylator phenotypes and genotypes of polymorphic arylamine N-acetyltransferase in human liver.Semantic proximity Read ↗

Molecular genotyping for N-acetylation polymorphism in Japanese patients with colorectal cancer.Semantic proximity Read ↗

An improved method for genotyping of N-acetyltransferase polymorphism by polymerase chain reaction.Semantic proximity Read ↗

Rapid genotype method to distinguish frequent and/or functional polymorphisms in human N-acetyltransferase-1.Semantic proximity Read ↗

Correlation between acetylation phenotype and genotype in Chinese women.Semantic proximity Read ↗

Genotyping of N-acetylation polymorphism and correlation with procainamide metabolism.Semantic proximity Read ↗

Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver.Semantic proximity Read ↗

N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans.Semantic proximity Read ↗

Sequences and expression of alleles of polymorphic arylamine N-acetyltransferase of human liver.Semantic proximity Read ↗

Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes.Semantic proximity Read ↗

Predictors of N-acetyltransferase activity: should caffeine phenotyping and NAT2 genotyping be used interchangeably in epidemiological studies?Semantic proximity Read ↗

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.