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Article

Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan.

Developmental biology - 15 Apr 2010

Dumas Kathleen J, Guo Chunfang, Wang Xi, Burkhart Kirk B, Adams Elizabeth J, Alam Hena, Hu Patrick J

Abstract excerpt

Steroid hormone and insulin/insulin-like growth factor signaling (IIS) pathways control development and lifespan in the nematode Caenorhabditis elegans by regulating the activity of the nuclear receptor DAF-12 and the FoxO transcription factor DAF-16, respectively. The DAF-12 ligands Delta(4)- an...

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Identifiers

PMID: 20178781
DOI: 10.1016/j.ydbio.2010.02.022
PMCID: PMC4511482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20178781-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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