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Article

DISC1 at 10: connecting psychiatric genetics and neuroscience.

Trends in molecular medicine - 1 Dec 2011

Porteous David J, Millar J Kirsty, Brandon Nicholas J, Sawa Akira

Abstract excerpt

Psychiatric genetics research, as exemplified by the DISC1 gene, aspires to inform on mental health etiology and to suggest improved strategies for intervention. DISC1 was discovered in 2000 through the molecular cloning of a chromosomal translocation that segregated with a spectrum of major mental illnesses in a single large Scottish family. Through in vitro experiments and mouse models, DISC1 has been firmly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22015021
DOI: 10.1016/j.molmed.2011.09.002
PMCID: PMC3253483

Genes

DISC1

Provenance

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