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Article

Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia.

Molecular psychiatry - 1 Jun 2012

Mathieson I, Munafò M R, Flint J

Abstract excerpt

Several polymorphisms in the Disrupted-in-Schizophrenia-1 (DISC1) gene are reported to be associated with schizophrenia. However, to date, there has been little effort to evaluate the evidence for association systematically. We carried out an imputation-driven meta-analysis, the most comprehensive to date, using data collected from 10 candidate gene studies and three genome-wide association studies containing a...

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Identifiers

PMID: 21483435
DOI: 10.1038/mp.2011.41
PMCID: PMC3359642

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

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Research trail→

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Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia.PMID 21483435Read ↗

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708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.Semantic proximity Read ↗

Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample.Semantic proximity Read ↗

Meta-analysis of association studies between DISC1 missense variants and schizophrenia in the Japanese population.Semantic proximity Read ↗

Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population.Semantic proximity Read ↗

Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophrenia.Semantic proximity Read ↗

Association study of DISC1 genetic variants with the risk of schizophrenia.Semantic proximity Read ↗

Lack of association between DISC1 polymorphisms and risk of schizophrenia in a Korean population.Semantic proximity Read ↗

Association study of polymorphisms in the 5' upstream region of human DISC1 gene with schizophrenia.Semantic proximity Read ↗

Genetic association between schizophrenia and the DISC1 gene in the Scottish population.Semantic proximity Read ↗

Association analysis of the DISC1 gene with schizophrenia in the Japanese population and DISC1 immunoreactivity in the postmortem brain.Semantic proximity Read ↗

Gene polymorphisms of DISC1 is associated with schizophrenia: Evidence from a meta-analysis.Semantic proximity Read ↗

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