Article
Characterization of seizure-like events recorded in vivo in a mouse model of Rett syndrome.
Neural networks : the official journal of the International Neural Network Society - 1 Oct 2013
Colic Sinisa, Wither Robert G, Zhang Liang, Eubanks James H, Bardakjian Berj L
Abstract excerpt
Rett syndrome is a neurodevelopmental disorder caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MECP2). Spontaneous recurrent discharge episodes are displayed in Rett-related seizures as in other types of epilepsies. The aim of this paper is to investigate the seizure-like event (SLE) and inter-SLE states in a female MeCP2-deficient mouse model of Rett syndrome and compare them to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
