Article

Early EEG and behavioral alterations in Dravet mice

2020-01-14

Abstract excerpt

Dravet Syndrome (Dravet) is a severe childhood epileptic encephalopathy. The disease begins around the age of six months, with a febrile stage, characterized by febrile seizures with otherwise normal development. By the end of the first year of life, the disease progresses to the worsening stage, featuring recurrent intractable seizures and the appearance of additional comorbidities, including global developmental...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b022f03b-ab8a-50d3-af41-357b5c3ecb64
DOI: 10.1101/2020.01.13.904557

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Early EEG and behavioral alterations in Dravet miceDOI 10.1101/2020.01.13.904557Read

Life-span characterization of epilepsy and comorbidities in Dravet syndrome mice carrying a targeted deletion of exon 1 of the Scn1a geneSemantic proximity Read

Sexual dimorphism in epilepsy and comorbidities in Dravet syndrome mice carrying a targeted deletion of exon 1 of the <i>Scn1a</i> geneSemantic proximity Read

Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to Low-Voltage-Fast onset seizures in Dravet syndromeSemantic proximity Read

Acute effect of antiseizure drugs on background oscillations in <i>Scn1a</i> <sup>A1783V</sup> Dravet syndrome mouse modelSemantic proximity Read

Early Developmental EEG and Seizure Phenotypes in a Full Gene Deletion of Ubiquitin Protein Ligase E3A Rat Model of Angelman Syndrome.Semantic proximity Read

A novel rat model of Dravet syndrome recapitulates clinical hallmarksSemantic proximity Read

Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development.Semantic proximity Read

Epilepsy and neuropsychiatric comorbidities in mice carrying a recurrent Dravet syndrome SCN1A missense mutationSemantic proximity Read

Dravet Syndrome: Past, Present, and Future.Semantic proximity Read

Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J BackgroundSemantic proximity Read

GABAergic signaling promotes early-life seizures in epileptic SYNGAP1 <sup>+/-</sup> miceSemantic proximity Read

A hyperthermic seizure unleashes a surge of spreading depolarizations in <i>Scn1a</i> deficient miceSemantic proximity Read