Article
Multiple sclerosis susceptibility alleles in African Americans.
Genes and immunity - 1 Jun 2010
Johnson B A, Wang J, Taylor E M, Caillier S J, Herbert J, Khan O A, Cross A H, De Jager P L, Gourraud P-A F, Cree B C A, Hauser S L, Oksenberg J R
Abstract excerpt
Multiple sclerosis (MS) is an autoimmune demyelinating disease characterized by complex genetics and multifaceted gene-environment interactions. Compared to whites, African Americans have a lower risk for developing MS, but African Americans with MS have a greater risk of disability. These differences between African Americans and whites may represent differences in genetic susceptibility and/or environmental...
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