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Article

Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.

Journal of human genetics - 1 Nov 2009

Hoppenbrouwers Ilse A, Aulchenko Yurii S, Janssens A Cecile, Ramagopalan Sreeram V, Broer Linda, Kayser Manfred, Ebers George C, Oostra Ben A, van Duijn Cornelia M, Hintzen Rogier Q

Abstract excerpt

A recent genome-wide association study by the International Multiple Sclerosis Genetics Consortium (IMSGC) reported association of 17 single-nucleotide polymorphisms (SNPs) in 14 loci with multiple sclerosis (MS). Only two loci, HLA-DRA and IL2RA, reached genome-wide significance (P<5E-08). In our study, we determined whether we could replicate the results of the IMSGC and whether more SNPs are genome-wide...

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PMID: 19834503
DOI: 10.1038/jhg.2009.96

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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