Article
No influence on disease progression of non-HLA susceptibility genes in MS.
Journal of neuroimmunology - 15 Aug 2011
Lundström Wangko, Greiner Eva, Lundmark Frida, Westerlind Helga, Smestad Cathrine, Lorentzen Aslaug R, Kockum Ingrid, Link Jenny, Brynedal Boel, Celius Elisabeth G, Harbo Hanne F, Masterman Thomas, Hillert Jan
Abstract excerpt
Recently, several non-HLA loci have been shown to be convincingly associated with Multiple Sclerosis (MS) susceptibility, assumingly indicating important pathways in the pathogenesis. A genotype influence on disease outcome measures by these genes would support a role of these pathways in ongoing tissue damage. Here, however, we report a consistent dissociation between causation and progression for five non-HLA...
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