Meta-analysis of the Selected Genetic Variants in Immune-Related Genes and Multiple Sclerosis Risk.

doi:10.1007/s12035-024-04095-7

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Article

Meta-analysis of the Selected Genetic Variants in Immune-Related Genes and Multiple Sclerosis Risk.

Molecular neurobiology - 1 Oct 2024

Zhou Weiguang, Hu Weiqiong, Tang Lingyu, Ma Xiaorui, Liao Jiaxi, Yu Zhiyan, Qi Meifang, Chen Bifeng, Li Jing

Abstract excerpt

Previous studies have suggested that certain variants in immune-related genes may participate in the pathogenesis of multiple sclerosis (MS), including rs17824933 in the CD6 gene, rs1883832 in the CD40 gene, rs2300747 in the CD58 gene, rs763361 in the CD226 gene, rs16944 in the IL-1β gene, rs2243250 in the IL-4 gene, and rs12722489 and in the IL-2Rα gene. However, the results remained inconclusive and...

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PMID: 38478144
DOI: 10.1007/s12035-024-04095-7

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Topics

Humans
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD40 Antigens
CD58 Antigens
Genetic Predisposition to Disease
Genetic Variation
Interleukin-1beta
Interleukin-4
Multiple Sclerosis
Polymorphism, Single Nucleotide
Publication Bias
Risk Factors
T Lineage-Specific Activation Antigen 1