Article
High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells.
Cardiovascular diabetology - 29 May 2013
Lu Hao, Yao Kang, Huang Dong, Sun Aijun, Zou Yunzeng, Qian Juying, Ge Junbo
Abstract excerpt
BACKGROUND: Both hyperglycaemia and dendritic cells (DCs) play causative roles in atherosclerosis. However, whether they interact in atherosclerosis remains uncertain. Therefore, we examined whether high glucose could regulate the expression of scavenger receptors responsible for oxidised low-density lipoprotein (oxLDL) uptake in DCs, a critical step in atherogenesis. In addition, we investigated the impact of...
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