Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxysterols induce transition of monocytic cells to phenotypically mature dendritic cell-like cells.

Biochemical and biophysical research communications - 16 Aug 2013

Son Yonghae, Kim Sun-Mi, Lee Sae-A, Eo Seong-Kug, Kim Koanhoi

Abstract excerpt

Dendritic cells (DCs) activate adaptive immune responses in atherosclerotic plaques; however, the origin of DCs is in question. We attempted to determine whether cholesterol or its oxide forms, which are detected in abundance in atheromatous lesions, could induce differentiation or transition of monocytic cells to DCs. Treatment of THP-1 cells with 27-hydroxycholesterol (27OH-Chol) and 7α-hydroxycholesterol...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Cell Differentiation
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to CCR7 gene

Share to Hydroxycholesterols

Share to Monocytes

Share to Phenotype

Source

Identifiers

PMID: 23876312
DOI: 10.1016/j.bbrc.2013.07.046

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxysterols induce transition of monocytic cells to phenotypically mature dendritic cell-like cells.PMID 23876312Read ↗

The effect of oxidized phospholipids on phenotypic polarization and function of macrophages.Semantic proximity Read ↗

oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation.Semantic proximity Read ↗

Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.Semantic proximity Read ↗

Anti-atherogenic peptide Ep1.B derived from apolipoprotein E induces tolerogenic plasmacytoid dendritic cells.Semantic proximity Read ↗

Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesionsSemantic proximity Read ↗

Palmitate promotes monocyte atherogenicity via de novo ceramide synthesis.Semantic proximity Read ↗

Lipopolysaccharide can block the potential of monocytes to differentiate into dendritic cells.Semantic proximity Read ↗

Platonin modulates differentiation and maturation of human monocyte-derived dendritic cells.Semantic proximity Read ↗

Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients.Semantic proximity Read ↗

Effect of 1,25-dihydroxyvitamin D3 on induction of scavenger receptor and differentiation of 12-O-tetradecanoylphorbol-13-acetate-treated THP-1 human monocyte like cells.Semantic proximity Read ↗

High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells.Semantic proximity Read ↗

Nobiletin, a citrus flavonoid, suppresses phorbol ester‐induced expression of multiple scavenger receptor genes in THP‐1 human monocytic cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.