Article
Maturation-dependent expression of C1q-binding proteins on the cell surface of human monocyte-derived dendritic cells.
International immunopharmacology - 1 Mar 2003
Vegh Zsuzsa, Goyarts Earl C, Rozengarten Kimberly, Mazumder Amitabha, Ghebrehiwet Berhane
Abstract excerpt
The expression and cell surface levels of many important receptors are dependent on the maturation stage of dendritic cells (DCs), and related to the unique function of immature and mature DCs. In this report, we show for the first time that human monocyte-derived DCs express two types of C1q-receptors, gC1qR and cC1qR. Furthermore, immature DCs secrete detectable amount of C1q into the culture supernatant....
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