Article
Insulin resistance and obesity affect monocyte-derived dendritic cell phenotype and function.
Diabetes research and clinical practice - 1 Dec 2020
Paccosi Sara, Pala Laura, Cresci Barbara, Silvano Angela, Cecchi Marta, Caporale Roberto, Maria Rotella Carlo, Parenti Astrid
Abstract excerpt
AIM: Cardiovascular disease (CVD) is prevalent in women after menopause, which may be associated with obesity, insulin resistance and metaflammation. Despite the recognized role of immunological mechanisms in vascular remodeling, the role of dendritic cells (DCs) is still unclear. The aim was to characterize monocyte-derived DCs (Mo-DC) in post-menopausal patients with type 2 diabetes (T2DM) and obese woman,...
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