Article
oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation.
Atherosclerosis - 1 Aug 2009
Nickel Thomas, Schmauss Daniel, Hanssen Henner, Sicic Zelka, Krebs Bjarne, Jankl Sarika, Summo Claudia, Fraunberger Peter, Walli Autar K, Pfeiler Susanne, Weis Michael
Abstract excerpt
BACKGROUND: Several studies have proposed a pathogenic role for oxidized LDL (oxLDL) in atherosclerosis. We tested the hypothesis whether oxLDL modulates dendritic cells (DCs), since these important antigen-presenting cells have been implicated in atherogenesis. We investigated the uptake of oxLD...
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