Article
Differentiation of bone marrow-derived endothelial progenitor cells is shifted into a proinflammatory phenotype by hyperglycemia.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2000
Loomans Cindy Jm, van Haperen Rien, Duijs Jacques M, Verseyden Caroline, de Crom Rini, Leenen Pieter Jm, Drexhage Hemmo A, de Boer Hetty C, de Koning Eelco Jp, Rabelink Ton J, Staal Frank Jt, van Zonneveld Anton Jan
Abstract excerpt
Bone marrow (BM)-derived endothelial progenitor cells (EPC) contribute to vascular maintenance by participating in angiogenesis, re-endothelialization, and remodeling. Myeloid progenitor cells in the BM are functionally and quantitatively an important precursor pool for cells that contribute to these processes. However, these precursor pools in the BM also give rise to important effector cells of the innate...
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