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Article

The influence of Ouabain on human dendritic cells maturation.

Mediators of inflammation - 1 Jan 2014

Nascimento C R, Valente R C, Echevarria-Lima J, Fontes C F L, de Araujo-Martins L, Araujo E G, Rumjanek V M

Abstract excerpt

Although known as a Na,K-ATPase inhibitor, several other cellular and systemic actions have been ascribed to the steroid Ouabain (Oua). Particularly in the immune system, our group showed that Ouabain acts on decreasing lymphocyte proliferation, synergizing with glucocorticoids in spontaneous thymocyte apoptosis, and also lessening CD14 expression and blocking CD16 upregulation on human monocytes. However,...

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Source

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Identifiers

PMID: 25609892
DOI: 10.1155/2014/494956
PMCID: PMC4291013

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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