Article
Association between Interleukin-23 Receptor R381Q Gene.
Iranian journal of allergy, asthma, and immunology - 1 Aug 2015
Mosayebian Ali, Ganjalikhani Hakemi Mazdak, Meshkat Rezvan, Ghasemi Ramin, Khan Ahmad Hossain, Samadi Morteza
Abstract excerpt
The SNP (rs11209026, Arg381Gln, R381Q) in the IL-23 receptor (IL23R) confers protection against multiple inflammatory diseases, representing one of the most significant human genetic polymorphisms in inflammatory diseases. We, therefore, investigated the association between IL-23 R R381Q gene polymorphism and asthma. This case-control study was performed on 209 patients, and 200 healthy controls. Using PCR-RFLP,...
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