Association between interleukin-27 gene polymorphisms and susceptibility to allergic rhinitis.

doi:10.1016/j.humimm.2014.07.004

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Article

Association between interleukin-27 gene polymorphisms and susceptibility to allergic rhinitis.

Human immunology - 1 Sept 2014

Shen Yang, Yuan Xiao-Dong, Hu Di, Ke Xia, Wang Xiao-Qiang, Hu Guo-Hua, Hong Su-Ling, Kang Hou-Yong

Abstract excerpt

OBJECTIVES: Allergic rhinitis (AR) is an inflammatory disorder of the upper airway. Interleukin-27 (IL-27), a novel IL-12 family member, has recently been reported to play a role in some immune-related disorders. This study was performed to evaluate the potential association of IL-27 polymorphisms with AR in a Chinese Han population. DESIGN AND METHODS: A case-control study was performed in 445 Chinese AR...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Asian People
Base Sequence
Case-Control Studies
Child
China
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-27

Linkage Disequilibrium

Male

Source

Open in PubMed

Identifiers

PMID: 25075448
DOI: 10.1016/j.humimm.2014.07.004

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