Article
Human papillomavirus tumor-infiltrating T-regulatory lymphocytes and P53 codon 72 polymorphisms correlate with clinical staging and prognosis of oropharyngeal cancer.
The new microbiologica - 1 Apr 2013
Rittà Massimo, Landolfo Vincenzo, Mazibrada Jasenka, De Andrea Marco, Dell'Oste Valentina, Caneparo Valeria, Peretti Alberto, Giordano Carlo, Pecorari Giancarlo, Garzaro Massimiliano, Landolfo Santo
Abstract excerpt
The association between human papillomavirus (HPV) DNA positivity, p53 codon 72 polymorphisms, and the type of leukocyte infiltration in head and neck squamous cell carcinomas (HNSCC) and their combined impact upon patient survival is poorly investigated. For this reason, leukocyte infiltration profile and p53 codon 72 polymorphisms were assessed in freshly removed HNSCC specimens (N=71 patients). HPV detection...
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