Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma.

Radiation oncology (London, England) - 11 May 2013

Xie Xiaoxue, Wang Hui, Jin Hekun, Ouyang Shuyu, Zhou Jumei, Hu Jun, Xi Xuping, Luo Junming, Zhang Yingying, Hu Bingqiang

Abstract excerpt

BACKGROUND: Codon 72 (Arg/Pro), the most frequently studied single nucleotide polymorphism (SNP) of p53 to date, is associated with the ability of the gene to induce cell apoptosis. The PI3K/Akt pathway plays an essential role in the transcriptional activation function of p53, and is an important...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Disease-Free Survival
Share to Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nasopharyngeal Carcinoma

Share to Nasopharyngeal Neoplasms

Share to Proportional Hazards Models

Share to Proto-Oncogene Proteins c-akt

Share to Radiation Tolerance

Source

Open in PubMed Open full text

Identifiers

PMID: 23663243
DOI: 10.1186/1748-717X-8-117
PMCID: PMC3720183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23663243-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma.PMID 23663243Read ↗

Association between p53 codon 72 polymorphisms and clinical outcome of nasopharyngeal carcinoma.Semantic proximity Read ↗

Association between the P53 codon 72 polymorphism and nasopharyngeal cancer risk.Semantic proximity Read ↗

Association between single nucleotide polymorphisms in the p53 pathway and response to radiotherapy in patients with nasopharyngeal carcinoma.Semantic proximity Read ↗

TP53 codon 72 polymorphism contributes to nasopharyngeal cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

The p53 codon 72 polymorphism in Thai nasopharyngeal carcinoma.Semantic proximity Read ↗

Associations of TP53 mutations, codon 72 polymorphism and human papillomavirus in head and neck squamous cell carcinoma patients.Semantic proximity Read ↗

p53 codon 72 polymorphism association with head and neck squamous cell carcinoma.Semantic proximity Read ↗

Association of p53 codon 72 polymorphism with risk of second primary malignancy in patients with squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Association between the TP53 codon 72 polymorphism and risk of oral squamous cell carcinoma in Asians: a meta-analysis.Semantic proximity Read ↗

Association of p53 and p21(CDKN1A/WAF1/CIP1) polymorphisms with oral cancer in Taiwan patients.Semantic proximity Read ↗

Association of p53 codon 72 polymorphism with risk of hypopharyngeal squamous cell carcinoma in Taiwan.Semantic proximity Read ↗

The p53 codon 72 polymorphism and the risk of oral cancer in a Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.