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Article

Combined p53-related genetic variants together with HPV infection increase oral cancer risk.

International journal of cancer - 1 Aug 2012

Wang Zhongqiu, Sturgis Erich M, Zhang Yang, Huang Zhigang, Zhou Qi, Wei Qingyi, Li Guojun

Abstract excerpt

To explore the role of polymorphisms of p53-related genes in etiology of oral cancer, we investigated joint effects of seven putatively functional polymorphisms of p53 (codon 72 Arg/Pro), p73 (4/14 GC/AT), murine double minute 2 gene (MDM2; A2164G and T2580G) and MDM4 (rs11801299 G > A, rs10900598 G > T and rs1380576 C > G) on risk of human papillomavirus (HPV)16-associated oral cancer in a case-control study...

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Share to Genes, p53
Share to Human papillomavirus 16
Share to Mouth Neoplasms
Share to Oropharyngeal Neoplasms
Share to Papillomavirus Infections
Share to Proto-Oncogene Proteins c-mdm2
Share to Tumor Protein p73
Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22052649
DOI: 10.1002/ijc.27335
PMCID: PMC3289741

Genes

MDM2
MDM4

Variants

rs11801299
rs11801299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Combined p53-related genetic variants together with HPV infection increase oral cancer risk.PMID 22052649Read ↗

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