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Article

Reduced hind limb ischemia-reperfusion injury in Toll-like receptor-4 mutant mice is associated with decreased neutrophil extracellular traps.

Journal of vascular surgery - 1 Dec 2013

Oklu Rahmi, Albadawi Hassan, Jones John E, Yoo Hyung-Jin, Watkins Michael T

Abstract excerpt

OBJECTIVE: Ischemia-reperfusion (IR) injury is a significant problem in the management of patients with acute limb ischemia. Despite rapid restoration of blood flow after technically successful open and endovascular revascularization, complications secondary to IR injury continue to occur and limit clinical success. Our aim was to create a murine model of hind limb IR injury to examine the role of Toll-like...

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Source

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Identifiers

PMID: 23683381
DOI: 10.1016/j.jvs.2013.02.241
PMCID: PMC3825746

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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