Back to search

Article

PGE <sub>2</sub> production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution <i>in vivo</i>

2017-10-19

Abstract excerpt

Neutrophils are the first immune cells recruited to a site of injury or infection, where they perform many functions. Having completed their role, neutrophils must be removed from the inflammatory site - either by apoptosis and efferocytosis or by reverse migration away from the wound - for restoration of normal tissue homeostasis. Disruption of these tightly controlled physiological processes of neutrophil remova...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a7ffd462-3f56-5ef7-8c34-234a4ce3f9fb
DOI
10.1101/205997
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PGE <sub>2</sub> production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution <i>in vivo</i>DOI 10.1101/205997
PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo.Semantic proximity
A nox2/cybb zebrafish mutant with defective myeloid cell reactive oxygen species production displays normal initial neutrophil recruitment to sterile tail injuries.Semantic proximity
A <i>nox2</i> / <i>cybb</i> zebrafish mutant with defective neutrophil ROS production displays normal initial neutrophil recruitment to sterile tail injuriesSemantic proximity
Using<i>in vivo</i>zebrafish models to understand the biochemical basis of neutrophilic respiratory diseaseSemantic proximity
Glucocorticoids inhibit macrophage differentiation towards a pro-inflammatory phenotype upon wounding without affecting their migrationSemantic proximity
Distinct macrophage phenotypes and redox environment during the fin fold regenerative process in zebrafish.Semantic proximity
Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model.Semantic proximity
The systemic inflammatory response induced by trauma is reflected by multiple phenotypes of blood neutrophils.Semantic proximity
Single-cell transcriptional landscape of temporal neutrophil response to burn wound in larval zebrafishSemantic proximity
Xenopus: An in vivo model for imaging the inflammatory response following injury and bacterial infectionSemantic proximity
Persistent CCL3 expression sustains neutrophil recruitment and contributes to delayed wound healing in advanced ageSemantic proximity
Peds1 deficiency in zebrafish results in myeloid cell apoptosis and exacerbated inflammationSemantic proximity
Select a neighboring publication to make it the new centre.