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Article

Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia.

Journal of human genetics - 1 Jun 2013

Yee Sook Wah, Mefford Joel A, Singh Natasha, Percival Mary-Elizabeth, Stecula Adrian, Yang Kuo, Witte John S, Takahashi Atsushi, Kubo Michiaki, Matsuda Koichi, Giacomini Kathleen M, Andreadis Charalambos

Abstract excerpt

Acute myeloid leukemia (AML) is a clinically heterogeneous disease, with a 5-year disease-free survival (DFS) ranging from under 10% to over 70% for distinct groups of patients. At our institution, cytarabine, etoposide and busulfan are used in first or second remission patients treated with a two-step approach to autologous stem cell transplantation (ASCT). In this study, we tested the hypothesis that...

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Share to Cytarabine
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glutathione Transferase

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Share to Leukemia, Myeloid, Acute

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Source

Open in PubMed Open full text

Identifiers

PMID: 23677058
DOI: 10.1038/jhg.2013.38
PMCID: PMC4068832

Genes

ABCC3
GSTM1
GSTM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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