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Article

Predictive potential of ABCB1, ABCC3, and GSTP1 gene polymorphisms on osteosarcoma survival after chemotherapy.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2014

Liu Shizhang, Yi Zhi, Ling Ming, Shi Jiyuan, Qiu Yusheng, Yang Shujuan

Abstract excerpt

Genetic polymorphisms in drug metabolism and transport genes can influence the pharmacokinetics and pharmacodynamics of chemotherapy drugs. We investigated the role of genes involved in metabolic and transport pathways in response to chemotherapy and clinical outcome of osteosarcoma patients. The association between the eight polymorphisms with response to chemotherapy and clinical outcome of patients was carried...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to Bone Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Glutathione S-Transferase pi

Share to Kaplan-Meier Estimate

Share to Multidrug Resistance-Associated Proteins

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Source

Identifiers

PMID: 24996541
DOI: 10.1007/s13277-014-1917-x

Genes

ABCB1
GSTP1
ABCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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