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Article

Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.

PloS one - 1 Jan 2011

Caronia Daniela, Patiño-Garcia Ana, Peréz-Martínez Antonio, Pita Guillermo, Moreno Leticia Tais, Zalacain-Díez Marta, Molina Blanca, Colmenero Isabel, Sierrasesúmaga Luis, Benítez Javier, Gonzalez-Neira Anna

Abstract excerpt

BACKGROUND: Standard treatment for osteosarcoma patients consists of a combination of cisplatin, adriamycin, and methotrexate before surgical resection of the primary tumour, followed by postoperative chemotherapy including vincristine and cyclophosphamide. Unfortunately, many patients still relapse or suffer adverse events. We examined whether common germline polymorphisms in chemotherapeutic transporter and...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22016816
DOI: 10.1371/journal.pone.0026091
PMCID: PMC3189235

Genes

ABCB1
ABCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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