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Article

Association of ABCB1 polymorphisms with prognostic outcomes of anthracycline and cytarabine in Chinese patients with acute myeloid leukemia.

European journal of clinical pharmacology - 1 Mar 2015

He Hui, Yin Jiye, Li Xi, Zhang Yu, Xu Xiaojing, Zhai Ming, Chen Juan, Qian Chenyue, Zhou Honghao, Liu Zhaoqian

Abstract excerpt

PURPOSE: To investigate the influence of ABCB1 polymorphisms on prognostic outcomes in Chinese patients with de novo intermediate-risk acute myeloid leukemia (AML) and to examine the gene expression level in relation to the genetic variation. METHODS: In total, 263 Chinese intermediate-risk AML patients treated with anthracycline and cytarabine were enrolled. G2677T, C1236T, and C3435T of the ABCB1 gene were...

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Share to Anthracyclines
Share to Antimetabolites, Antineoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B

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Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 25567217
DOI: 10.1007/s00228-014-1795-6

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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