Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26.

PloS one - 1 Jan 2012

McAuley Erica Z, Scimone Anna, Tiwari Yash, Agahi Giti, Mowry Bryan J, Holliday Elizabeth G, Donald Jennifer A, Weickert Cynthia Shannon, Mitchell Phillip B, Schofield Peter R, Fullerton Janice M

Abstract excerpt

We previously identified a significant bipolar spectrum disorder linkage peak on 15q25-26 using 35 extended families with a broad clinical phenotype, including bipolar disorder (types I and II), recurrent unipolar depression and schizoaffective disorder. However, the specific gene(s) contributing to this signal had not been identified. By a fine mapping association study in an Australian case-control cohort...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Genetic Loci

Share to Mood Disorders

Share to Prefrontal Cortex

Share to Psychotic Disorders

Share to Sialyltransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 22693595
DOI: 10.1371/journal.pone.0038172
PMCID: PMC3364966

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26.PMID 22693595Read ↗

Characterization of a 520 kb deletion on chromosome 15q26.1 including ST8SIA2 in a patient with behavioral disturbance, autism spectrum disorder, and epilepsy.Semantic proximity Read ↗

Characterisation of genetic variation in ST8SIA2 and its interaction region in NCAM1 in patients with bipolar disorder.Semantic proximity Read ↗

Association between ST8SIA2 and the Risk of Schizophrenia and Bipolar I Disorder across Diagnostic Boundaries.Semantic proximity Read ↗

Genomic mapping and cellular expression of human CPG2 transcripts in the SYNE1 gene.Semantic proximity Read ↗

Impact of structural aberrancy of polysialic acid and its synthetic enzyme ST8SIA2 in schizophreniaSemantic proximity Read ↗

Genome-wide scan supports the existence of a susceptibility locus for schizophrenia and bipolar disorder on chromosome 15q26.Semantic proximity Read ↗

Effects of intronic single nucleotide polymorphisms (iSNPs) of a polysialyltransferase, ST8SIA2 gene found in psychiatric disorders on its gene products.Semantic proximity Read ↗

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus.Semantic proximity Read ↗

Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.Semantic proximity Read ↗

Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder.Semantic proximity Read ↗

A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26.Semantic proximity Read ↗

Association of rare variation in the glutamate receptor gene SLC1A2 with susceptibility to bipolar disorder and schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.