Article
MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases.
Annals of surgery - 1 Jun 2013
Isella Claudio, Mellano Alfredo, Galimi Francesco, Petti Consalvo, Capussotti Lorenzo, De Simone Michele, Bertotti Andrea, Medico Enzo, Muratore Andrea
Abstract excerpt
OBJECTIVE: Upon colon cancer metastasis resection in liver, disease outcome is heterogeneous, ranging from indolent to very aggressive, with early recurrence. The aim of this study is to investigate the capability of metastasis associated in colon cancer 1 (MACC1) levels measured in liver metastasis specimens to predict further recurrence of the disease. METHODS: Gene expression and gene dosage of MACC1,...
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