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Article

High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.

Molecular cancer - 14 Feb 2015

Ilm Katharina, Kemmner Wolfgang, Osterland Marc, Burock Susen, Koch Gudrun, Herrmann Pia, Schlag Peter M, Stein Ulrike

Abstract excerpt

BACKGROUND: The metastasis-associated in colon cancer 1 (MACC1) gene has been identified as prognostic biomarker for colorectal cancer (CRC). Here, we aimed at the refinement of risk assessment by separate and combined survival analyses of MACC1 expression with any of the markers KRAS mutated in...

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Identifiers

PMID: 25742883
DOI: 10.1186/s12943-015-0316-2
PMCID: PMC4335361

Genes

KRAS
MACC1
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25742883-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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