Article
Single nucleotide polymorphisms in the metastasis-associated in colon cancer-1 gene predict the recurrence of hepatocellular carcinoma after transplantation.
International journal of medical sciences - 1 Jan 2014
Zheng Zhiyun, Gao Sheng, Yang Zhe, Xie Haiyang, Zhang Cheng, Lin Bingyi, Wu Liming, Zheng Shusen, Zhou Lin
Abstract excerpt
BACKGROUND: The newly identified metastasis-associated in colon cancer-1 (MACC1) gene is involved in angiogenesis, epithelial-to-mesenchymal transition (EMT), invasiveness, and metastasis in a variety of malignancies. Overexpression of MACC1 gene is a prognostic marker for poor outcome of hepatocellular carcinoma (HCC) patients. However, the association between genetic polymorphisms of MACC1 gene and poor outcome...
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