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Article

Host MICA Polymorphism as a Potential Predictive Marker in Response to Chemotherapy for Colorectal Liver Metastases.

Digestive diseases (Basel, Switzerland) - 1 Jan 2018

Nishioka Yujiro, Shindoh Junichi, Inagaki Yoshinori, Gonoi Wataru, Mitsui Jun, Abe Hiroyuki, Yoshioka Ryuji, Yoshida Shuntaro, Fukayama Masashi, Tsuji Shoji, Hashimoto Masaji, Hasegawa Kiyoshi, Kokudo Norihiro

Abstract excerpt

BACKGROUND: Understanding the genetic background of a tumor is important to better stratify patient prognosis and select optimal treatment. For colorectal liver metastases (CLM), however, clinically available biomarkers remain limited. METHODS: After a comprehensive sequencing of 578 cancer-related genes in 10 patients exhibiting very good/poor responses to chemotherapy, the A5.1 variant of the MICA gene was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29969766
DOI: 10.1159/000490411

Genes

MICA
EGFR

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