Article
SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
Molecular cancer - 29 Jul 2012
Schmid Felicitas, Burock Susen, Klockmeier Konrad, Schlag Peter M, Stein Ulrike
Abstract excerpt
BACKGROUND: Colorectal cancer is one of the main cancers in the Western world. About 90% of the deaths arise from formation of distant metastasis. The expression of the newly identified gene metastasis associated in colon cancer 1 (MACC1) is a prognostic indicator for colon cancer metastasis. Here, we analyzed for the first time the impact of single nucleotide polymorphisms (SNPs) in the coding region of MACC1...
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