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Article

Effect of Co-mutation of RAS and TP53 on Postoperative ctDNA Detection and Early Recurrence after Hepatectomy for Colorectal Liver Metastases.

Journal of the American College of Surgeons - 1 Apr 2022

Nishioka Yujiro, Chun Yun Shin, Overman Michael J, Cao Hop S Tran, Tzeng Ching-Wei D, Mason Meredith C, Kopetz Scott W, Bauer Todd W, Vauthey Jean-Nicolas, Newhook Timothy E

Abstract excerpt

BACKGROUND: Circulating tumor DNA (ctDNA) is a promising biomarker for patients undergoing hepatectomy for colorectal liver metastases (CLM). We hypothesized that post-hepatectomy ctDNA detection would identify patients at highest risk for early recurrence of CLM. STUDY DESIGN: Patients with CLM who underwent curative-intent hepatectomy with ctDNA analysis within 180 days postoperatively (1/2013 and 6/2020) were...

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Share to Circulating Tumor DNA
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

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Identifiers

PMID: 35290266
DOI: 10.1097/XCS.0000000000000093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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